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Why can Ganoderma effectively treat hypertension
2016-09-06   Source:    Hit:1991   Font: 
Pharmacological studies indicate that Ganoderna has anti-hypertension effect. On the spontaneously hypertension rats, feeding Ganoderam mycelium powder significantly decreased their blood pressure and cholesterol in liver and plasma. A recent study reported that Ganoderma polysaccharides lowered the superoxide in aortic vascular smooth muscles of hypertension rats to the normal level, and elevated the superoxide dismutase activity. These results suggest that the anti-oxidative and free radical-scavenging activities of Ganoderma are associated with its efficacy in treating hypertension.                                                                                                                                                                                                                                                                                                                                                                                               At present, Ganoderma's anti-hypertension effect is believed to relate to triterpenoids it contains. For instance, 5 triterpenoid compounds isolated from the 70% methanol extract of Ganoderma lucidum, i.e., ganoderic acid A, K and S, and ganoderol A and B, showed the inhibitory activity on angiotensin-converting enzyme (AVE). high ACE activity can lead to rise on blood pressure. Thus, by suppressing ACE activity, the triterpenoids can indirectly reduce symptoms of hypertension.
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